Which of the following is a post-translational modification?

Study for the A2 Genetic Control of Proteins Test. Engage with flashcards and multiple choice questions, each question is accompanied by hints and explanations. Prepare thoroughly for your exam!

Multiple Choice

Which of the following is a post-translational modification?

Explanation:
Post-translational modification refers to chemical changes made to a protein after it has been synthesized. Phosphorylation is a classic example: kinases attach a phosphate group to specific amino acids (such as serine, threonine, or tyrosine). This covalent addition can rapidly change a protein’s activity, interactions, location, or stability, and it’s reversible, allowing dynamic control of signaling pathways. mRNA splicing edits the RNA transcript before translation, not the protein. DNA replication duplicates genetic material, unrelated to modifying a protein after it’s made. Protein folding describes how the polypeptide adopts its three-dimensional shape during synthesis, not a chemical modification of the protein itself.

Post-translational modification refers to chemical changes made to a protein after it has been synthesized. Phosphorylation is a classic example: kinases attach a phosphate group to specific amino acids (such as serine, threonine, or tyrosine). This covalent addition can rapidly change a protein’s activity, interactions, location, or stability, and it’s reversible, allowing dynamic control of signaling pathways.

mRNA splicing edits the RNA transcript before translation, not the protein. DNA replication duplicates genetic material, unrelated to modifying a protein after it’s made. Protein folding describes how the polypeptide adopts its three-dimensional shape during synthesis, not a chemical modification of the protein itself.

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