What happens to CAP activation when glucose is abundant?

Study for the A2 Genetic Control of Proteins Test. Engage with flashcards and multiple choice questions, each question is accompanied by hints and explanations. Prepare thoroughly for your exam!

Multiple Choice

What happens to CAP activation when glucose is abundant?

Explanation:
CAP activation depends on binding of cAMP to CAP. When glucose is abundant, production of cAMP drops because adenylyl cyclase is inhibited. With little or no cAMP, CAP cannot effectively bind to its target promoter and recruit RNA polymerase, so transcription that requires CAP activation is reduced. This is the reason CAP activation decreases when glucose is plentiful.

CAP activation depends on binding of cAMP to CAP. When glucose is abundant, production of cAMP drops because adenylyl cyclase is inhibited. With little or no cAMP, CAP cannot effectively bind to its target promoter and recruit RNA polymerase, so transcription that requires CAP activation is reduced. This is the reason CAP activation decreases when glucose is plentiful.

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